Serena Campbell walked away from Holby City last night, and fans were gutted to see her go.
On Tuesday (January 21), actress Catherine Russell's character Serena departed the medical drama after eight years, marking the end of an era for the hospital.
Serena's momentous decision came after turbulent scenes in which she was arrested.
The consultant general surgeon joined forces with Sacha, Jac and Fletch as they spearheaded 'the resistance' against Max's plans to privatise hospital services.
Why am I crying? I'm going to miss Serena.
Although she was wary about the whole thing, Serena ended up getting herself into big trouble when she got involved in a bid to call off the porters' strike - and got on the wrong side of the law.
Upon her return to Holby, Serena was promptly sacked by Max for gross misconduct and had a small farewell gathering at the Wyvern entrance.
Telling her former colleagues what she might do next, she said: "There might be a job for me in Kenya, I might do that. Or I might move to Cornwall and grow marrows. Or run for Parliament. Or write a book. I am woman, hear me roar!"
Fans were upset to see Serena leave, with one typing: "It was tremendously sad to see Serena going, but wish Catherine all the best for her future."
Another said: "Come on, be honest Holby fans, who didn't have a tear in their eye at the end of Holby tonight? I hope that Serena's comment at the end maybe hopefully mean she might be back, wow what amazing acting from Catherine Russell."
A third added: "Why am I crying? I'm going to miss Serena, she was brilliant tonight. She's one determined lady. Holby won't be the same without her."
"Going to miss you Serena. Had tears in my eyes. Hope you come back soon," added one more.
Speaking to Digital Spy about Serena's final episode, actress Catherine, 54, revealed she might well be back one day.
She said: "I'm more than delighted and deeply flattered that one of Serena's last lines was that she'd never be so far away that she couldn't come back when she's needed.
"When I saw that, I thought: 'That is an extremely generous and kind thing to write.' I shall remind them of it, possibly, in the future, when I go running back with my tail very firmly between my legs!
"I'd never say never. I'd never want to slam the door behind myself, that would be foolish."
She revealed she was leaving to "test the waters [and] go and scare myself again".
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