The beloved duo will enjoy almost two months off to spend time with their families over the summer.
Making a special appearance on the daytime show on Friday - which is usually hosted by Eamonn and Ruth - Holly and Phil announced it was their last show for the summer.
Phil said: "It's our last show before we go on our summer break... [Holly's] head's already on a lounger somewhere."
Holly added: "But don't worry Eamonn and Ruth will be be here to take you right through until September."
It's believed that husband and wife duo Eamonn and Ruth will host the show Monday to Thursday, while another presenting pair will take over Fridays.
Earlier today, Holly shared a snap of her outfit for the show as she expressed her excitement about her time off.
Eamonn and Ruth will be be here to take you right through until September.View this post on Instagram
The presenter wore a stunning - and very summery - floral dress by Fenwick with a pair of black heels by Office.
She captioned the post: "Morning Fri-yay!!! Don’t get to say that very often... today’s final #hwstyle before we break up for summer here on @thismorning."
Fans were gutted it was Holly and Phil's last day and shared their thoughts in the comments section.
One person said: "Six weeks without your input on television is like a prison sentence," while another wrote: "Noooo I will miss you guys.. have a great summer."
A third commented: "Love you guys, enjoy your time off, won't be the same without you."
This will be the first time Ruth is back on TV following the death of her sister Julia.
The Loose Women panellist has taken a break from work after Julia passed away "after a very long illness".
My lovely Sis Julia has sadly died after a very long illness. My heart is completely broken. She was the kindest and most gentle soul and I will miss her forever. As I am sure you will appreciate I need to take time to grieve with my family. Thank you for your understanding. pic.twitter.com/o6jMtIqMg4
— Ruth Langsford (@RuthieeL) 20 June 2019
She wrote on Twitter last month: "My lovely Sis Julia has sadly died after a very long illness. She was the kindest and most gentle soul and I will miss her forever.
"As I am sure you will appreciate I need to take time to grieve with my family. Thank you for your understanding."
Will you miss Holly and Phil? Are you looking forward to watching Eamonn and Ruth over the summer? Let us know over on our Facebook page @EntertainmentDailyFix.